Hepatitis B is an inflammation of the liver caused by hepatitis B (HВV), which uses the liver cells to build new virus particles that causes significant liver damage. Therefore, blood biochemical parameters (liver function tests) in the stage of acute infection increased ten times from normal values. Hepatitis B is a dangerous severe course and transition to chronic infection in 5-10% of all cases. The risk of developing chronic infection is much higher in young children under the age of 5 years. 20% of patients with chronic viral hepatitis b, is formed cirrhosis of the liver. 5% liver cancer.
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hepatitis B is often detected along with the hepatitis d Virus (Delta hepatitis) is the smallest member of viral hepatitis, which can cause inflammation of the liver alone and is always accompanied by hepatitis B, with complications over the past. For this reason, it is correct to consider hepatitis B and D together as one disease where the virus is Delta (D) is a factor in aggravating hepatitis B.
hepatitis b Virus is very contagious, given the harm, all developed countries have adopted programs of mandatory vaccination (immunization) against hepatitis b, to reduce the incidence of several times.
hepatitis B Virus is present in all biological fluids of a sick person, but through intact skin hepatitis B virus does not penetrate. This fact suggests that household contact, through hepatitis b is not transmitted. One day refresher of viral hepatitis b, you cannot catch it again. Also, a guarantee of protection against hepatitis b is vaccination (vaccination against hepatitis b).
the First signs of disease appear not earlier than six months after infection with hepatitis B. at First concerned about the weakness and poor appetite. Then nausea, abdominal pain, heaviness in the right hypochondrium, slight fever, joint pain (often severe), and muscle aches. Gradually, the disease becomes the height of the so-called icteric period. The sclera turns yellow, worried about itching, dark urine, lighter stools. In one third of all cases of hepatitis b occurs without any symptoms. Many of the symptoms of viral hepatitis (link) similar. To determine the type of virus causing hepatitis by blood tests.
HBsAg (HBs-antigen, on the other "Australian" antigen) is a blood test always be performed to check for hepatitis B. Different combinations listed below are the specific markers of viral hepatitis B suggest the presence of infection in the present and the past. Such markers help to identify acute or chronic phase of hepatitis b, testify to the activity of the virus. According to the results of blood tests for specific markers it is possible to determine the indications for treatment, and evaluate therapy efficacy. We present these tests as evidence of the need for regular monitoring, which is based on modern treatment of viral hepatitis B.
During the initial stage of acute hepatitis B, which precedes the beginning of the so-called icteric period in serum detect the following markers: HBsAg, HBeAg, HBV-DNA and IgM anti-HBC. These tokens can not constantly be determined during the height of all the symptoms of acute hepaitis B. under reducing manifestations of the disease detects IgM anti-HBc, anti-HBe and, later, anti-HBc (total) and IgG anti-HBc. Detection of HBeAg, in the absence of anti-HBe is a sign of transition of the infection in chronic form. The appearance of anti-HBs in the period, and the disappearance of HBsAg in blood is a good sign and indicator of recovery. The detection of hepatitis B to correctly perform a blood test for determination of hepatitis D virus (HDV-RNA), as well as hepatitis D is a frequent companion of viral hepatitis b and complicates the past.
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